RecruitingNCT03101813

International Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry and Repository


Sponsor

Children's Hospital Medical Center, Cincinnati

Enrollment

1,500 participants

Start Date

Jun 1, 2012

Study Type

OBSERVATIONAL

Conditions

Summary

Doctors and other medical scientists want learn about the biology of DIPG/DMG and to develop better ways to diagnose and treat patients with DIPG/DMG. To do this, they need more information about the characteristics of DIPG/DMG tumors. Therefore, they want to establish a central location for clinical information and tumor tissue collected from DIPG/DMG patients. The purposes of this study are: * To enroll patients diagnosed with DIPG/DMG in the International DIPG/DMG Registry and Repository. * To provide a central location for clinical information, scans, and tissue samples from patients with DIPG/DMG enrolled in the registry. * To collect tissue samples in order to study how DIPG/DMG works on the molecular level. Researchers may use the tissue samples to study molecules such as proteins and DNA. Proteins are needed for the body to function properly and DNA is the molecule that carries our genetic information. Other researchers will be able to use the stored samples in the future to learn more about DIPG/DMG. The information researchers get from the research studies will be kept in the registry along with the clinical information. * To help investigators around the world to work together to make more consistent diagnosis and better design of future research studies. We hope this will lead to better treatments for DIPG/DMG in the future.


Eligibility

Plain Language Summary

Simplified for easier understanding

This is an international registry — a large database — collecting information about patients with DIPG (Diffuse Intrinsic Pontine Glioma) or Diffuse Midline Glioma, which are aggressive brain tumors often found in children. The goal is to gather data that can help researchers better understand and eventually find better treatments for these tumors. **You may be eligible if...** - You (or your child) have been diagnosed with DIPG or Diffuse Midline Glioma at any point — whether currently or in the past - This includes patients of any age, including those who have passed away (data can be submitted on their behalf) - If the patient is living, written consent from the patient or a parent/guardian is required **You may NOT be eligible if...** - You (or your child) have not been diagnosed with DIPG or Diffuse Midline Glioma - Consent cannot be provided by the patient or their legal guardian Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, United States

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NCT03101813


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