A Randomized Trial to Assess the Role of Imaging During Follow Up After Radical Surgery of High Risk Melanoma

This trial is studying whether regular imaging scans (like CT scans) during follow-up after surgery for high-risk melanoma (skin cancer) helps detect recurrence earlier and improves patient outcomes, compared to less frequent monitoring. **You may be eligible if...** - You are at least 18 years old - You have had surgery to remove high-risk melanoma (stage IIb, IIc, or stage III) - Your kidneys are working well enough to receive contrast dye used in imaging scans **You may NOT be eligible if...** - Your doctor believes you would not be a good candidate for further treatment if the cancer came back - You have another serious illness that means you are not expected to live more than 2 years (such as advanced heart disease, end-stage liver disease, or terminal MS) - You are unable or unwilling to provide consent - You cannot commit to the follow-up schedule - You are currently in another clinical trial that would interfere with this one - You have had another cancer diagnosis in the past 5 years (except for non-invasive breast or cervical cancer, melanoma in situ, or non-melanoma skin cancer) - You are pregnant or planning to become pregnant Talk to your doctor to see if this trial is right for you.