RecruitingNCT03131427

China Registry for Genetic / Metabolic Liver Diseases

A Nation-wide Hospital-based Registry:China Registry for Genetic / Metabolic Liver Diseases


Sponsor

Beijing Friendship Hospital

Enrollment

20,000 participants

Start Date

Jun 13, 2015

Study Type

OBSERVATIONAL

Conditions

Summary

CR-GMLD registry started on June 13, 2015 to collect cases of genetic/metabolic liver diseases from tertiary or secondary hospitals in mainland China. Demographics, diagnosis, laboratory test results, family history and prescriptions were recorded. Patients' whole blood and serum were collected for genetic testing and future researches. These patients will be followed-up every six to twelve months.


Eligibility

Inclusion Criteria1

  • Patients who were diagnosed or possibly diagnosed with Wilson's disease, hereditary hemochromatosis, hereditary hyperbilirubinemias, inherited cholestatic liver disease or other genetic/metabolic liver diseases.

Exclusion Criteria1

  • Patients who are unable or unwilling to provide informed consent.

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Interventions

DRUGStandard of care

Standard of care according to the updated national and/or international guidelines


Locations(12)

Beijing Ditan Hospital

Beijing, Beijing Municipality, China

Beijing Anzhen Hospital, Capital Medical University

Beijing, Beijing Municipality, China

Peking University First Hospital

Beijing, Beijing Municipality, China

Beijing YouAn Hospital

Beijing, Beijing Municipality, China

Nanfang Hospital of Southern Medical University

Guangzhou, Guangdong, China

Hebei Medical University Third Hospital

Shijiazhuang, Hebei, China

Henan Provincial Hospital

Zhengzhou, Henan, China

Zhongshan Hospital, Fudan University

Shanghai, Shanghai Municipality, China

Jinshan Hospital of Fudan University

Shanghai, Shanghai Municipality, China

West China Women's and Children's Hospital, Sichuan University

Chengdu, Sichuan, China

Affiliated Hospital, Logistics University of People's Armed Police Force

Tianjin, Tianjin Municipality, China

Xinjiang Uygur Autonomous Region Traditional Chinese Medicine Hospital

Ürümqi, Xinjiang, China

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NCT03131427