RecruitingNCT03192501

iCAGES-guided Precision Therapy for Cancers in Contrast to Standard Care or IHC-guided Theray

Multicentre Perspective Non-interventional Study of Survival Benefits of iCAGES-guided Therapy in Contrast to Standard Therapy or IHC-guided Therapy for Advanced Cancers


Sponsor

Second Affiliated Hospital of Guangzhou Medical University

Enrollment

250 participants

Start Date

Jul 1, 2017

Study Type

OBSERVATIONAL

Conditions

Summary

This study prospectively evaluates whether the use of iCAGES (integrated CAncer GEnome Score) tool in guiding the treatment of advanced cancers is superior to current standard care or IHC-guided therapy in progress free survival (PFS),overall survival (OS),and improvement of life quality.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether using a computer-based tool called iCAGES — which analyses a patient's tumour genes and medical images together — can guide doctors to better, more personalised cancer treatments for people with advanced or recurrent lung cancer or other advanced cancers. **You may be eligible if...** - You have been diagnosed with recurrent or metastatic lung cancer, or another advanced cancer - Your imaging records (CT/MRI scans) are available at the study hospital - You are between 18 and 70 years old - You are willing to sign a consent form **You may NOT be eligible if...** - You are over 70 or under 18 years old - You have a previous history of another malignant tumour - You are pregnant or breastfeeding - You have serious heart disease or other major conditions that could affect your prognosis Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGinhibitors, ADC drugs such as tarceva, capmatinib, padcev et al for A/C group.

Choose appropriate targeted drugs according to NGS/IHC results.


Locations(1)

The Second Affiliated Hospital of Guangzhou Medical University

Guangzhou, Guangdong, China

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NCT03192501


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