RecruitingNCT03210831

Early Predictors of Necrotizing Enterocolitis in Neonates

Clinical Model for Early Predictors of Necrotizing Enterocolitis in Neonates


Sponsor

Nationwide Children's Hospital

Enrollment

450 participants

Start Date

Sep 6, 2017

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this project is to identify neonates who are predisposed to Necrotizing Enterocolitis (NEC). the investigators will determine the effectiveness of non-invasive measures as well as biochemical markers to identify neonates early in the disease process. Thus, the investigators aim to identify infants with NEC prior to the onset of symptoms to institute or test treatments in the long term to prevent the progression of the disease in these infants.


Eligibility

Max Age: 7 Days

Plain Language Summary

Simplified for easier understanding

This study looks for early biological warning signs (biomarkers) that can predict which premature or very small newborns will develop necrotizing enterocolitis (NEC) — a serious and potentially life-threatening intestinal condition affecting premature infants. Earlier detection could allow for faster treatment and better survival rates. You may be eligible if: - Your baby was born at 30 weeks of pregnancy or earlier - OR your baby weighs 1,500 grams (about 3.3 lbs) or less at birth You may NOT be eligible if: - Your baby was born after 30 weeks of pregnancy and weighs more than 1,500 grams - Your baby has obvious genetic or physical abnormalities - Your baby has an abdominal wall defect (such as omphalocele or gastroschisis) - Your baby has a known intestinal blockage (intestinal atresia) - Your baby has complex heart defects - Your baby has a known lethal chromosomal condition Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Nationwide Children's Hospital

Columbus, Ohio, United States

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NCT03210831


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