RecruitingNCT03210831

Early Predictors of Necrotizing Enterocolitis in Neonates

Clinical Model for Early Predictors of Necrotizing Enterocolitis in Neonates


Sponsor

Nationwide Children's Hospital

Enrollment

450 participants

Start Date

Sep 6, 2017

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this project is to identify neonates who are predisposed to Necrotizing Enterocolitis (NEC). the investigators will determine the effectiveness of non-invasive measures as well as biochemical markers to identify neonates early in the disease process. Thus, the investigators aim to identify infants with NEC prior to the onset of symptoms to institute or test treatments in the long term to prevent the progression of the disease in these infants.


Eligibility

Max Age: 7 Days

Inclusion Criteria2

  • Infants born at ≤30 weeks gestational age and/or
  • Infants with a birth weight ≤1500 grams

Exclusion Criteria6

  • gestational age at birth greater than 30 weeks
  • obvious dysmorphic syndromes
  • any abdominal wall defect including omphalocele or gastroschisis
  • any known intestinal atresia
  • complex cardiac abnormalities
  • any known lethal chromosomal abnormalities

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Locations(1)

Nationwide Children's Hospital

Columbus, Ohio, United States

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NCT03210831


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