RecruitingNCT03223077

Mucosal and Microbiota Changes During Acute Campylobacteriosis

Sponsor

Mayo Clinic

Enrollment

150 participants

Start Date

Oct 31, 2014

Study Type

OBSERVATIONAL

Conditions

Irritable Bowel Syndrome

Summary

Gastrointestinal (GI) infection with Campylobacter causes inflammation in the bowel and can change bacteria in the gut. Certain individuals with Campylobacter infection are also known to develop chronic bowel problems such as Irritable Bowel Syndrome (IBS). The researchers are doing this study to understand if changes in gut bacteria and gut mucosal lining during an acute infection can help identify individuals who might be at risk for developing problems in the future.

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria2

No abdominal surgery (except appendectomy and cholecystectomy)
Stool culture or Polymerase chain reaction (PCR) positive enteritis with Campylobacter

Exclusion Criteria3

History of IBS, Irritable Bowel Disease (IBD) (Crohn's disease or ulcerative colitis), microscopic colitis or celiac disease.
History of gastroenteritis in six months prior to Campylobacter enteritis
Pregnancy

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