RecruitingNot ApplicableNCT03337932

Duration of Doxycycline Treatment in MEM Patients

Duration of Doxycycline Treatment in Patients With Multiple Erythema Migrans (MEM). A Randomized Clinical Trial


Sponsor

University Medical Centre Ljubljana

Enrollment

200 participants

Start Date

May 1, 2018

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to compare the efficacy of 7-day versus 14-day doxycycline treatment in patients with multiple erythema migrans.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • multiple erythema migrans

Exclusion Criteria5

  • pregnancy or lactation
  • immunocompromised
  • serious adverse event to doxycycline
  • taking antibiotic with antiborrelial activity within 10 days
  • extracutaneous manifestations of lyme borreliosis

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Interventions

DRUGDoxycycline 100 milligram Oral Tablet bid, 7 days

Patients will receive doxycycline for 7 days.

DRUGDoxycycline 100 milligram Oral Tablet bid, 14 days

Patients will receive doxycycline for 14 days.

DRUGControls without a history of lyme disease.

No intervention.


Locations(1)

University Medical center Ljubljana

Ljubljana, Slovenia

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NCT03337932