RecruitingPhase 4NCT03346772

Study of Immune Responses to Influenza Vaccination


Sponsor

University of Pennsylvania

Enrollment

75 participants

Start Date

Oct 20, 2017

Study Type

INTERVENTIONAL

Summary

Better understanding of the immune responses to influenza vaccination is needed in order to understand situations of poor vaccine response. Adults will receive influenza vaccination and then have peripheral blood drawn at pre-defined intervals in order to study the lymphocyte responses.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • Community-dwelling adults able to provide consent who need influenza vaccination for standard of care

Exclusion Criteria6

  • febrile illness at time of vaccination
  • active malignancy
  • use of immunosuppressing medications
  • blood donation in the past 60 days
  • influenza vaccinated during the preceding 6 months
  • allergic reactions to influenza vaccination

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Interventions

BIOLOGICALInfluenza vaccination

Adults will receive one intramuscular dose of seasonal quadrivalent inactivated influenza vaccine, as indicated for standard of care.


Locations(1)

University of Pennsylvania

Philadelphia, Pennsylvania, United States

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NCT03346772