RecruitingNCT03349762

Huaier Granules for Prevention of Recurrence and Metastasis of Colorectal Cancer Patients Following Radical Surgery

A Real-World Study Investigating Huaier Granules for Prevention of Recurrence and Metastasis of Colorectal Cancer Patients Following Radical Surgery


Sponsor

Xi Shan Wang

Enrollment

3,060 participants

Start Date

Nov 2, 2018

Study Type

OBSERVATIONAL

Conditions

Summary

To evaluate the efficacy and safety of Huaier granules for Prevention of Recurrence and Metastasis of colorectal cancer patients following radical surgery


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria5

  • Males or females ages 18-75 years;
  • The first time to the therapy of patients who received the radical surgery within two months, Postoperative histopathology confirms the diagnosis of colorectal cancer with stage IIB, IIC and III ( TNM classification)
  • ECOG score of 0-2;
  • No history of malignant tumors;
  • The patients are volunteered for the study, sign informed consent form and cooperate with Investigator to collect data.

Exclusion Criteria7

  • Patients have basic diseases including heart diseases, cerebrovascular disease, lung disease, severe hypertension or diabetes with poor glycemic control;
  • confirmed infections after surgery ;
  • Patients who have post-surgery complications or who are currently under the influence of the radical surgery for colorectal cancer;
  • Being infected with syphilis or with other blood-borne infectious diseases;
  • Pregnancy or lactation; or women of childbearing potential not using contraception;
  • Patients who have taken Traditional Chinese Medicines with efficacy and indications similar to that of Huaier granule - including, but not limited to, compound Banmao capsule., Huachansu capsule, Kangai Injection and Pingxiao tablets;
  • Patients who are suffering from mental illness or Conditions that are considered not suitable for this study investigators.

Locations(22)

The Fourth Hospital of Hebei Medical University

Shijiazhuang, Hebei, China

The First Clinical Hospital affiliated to Harbin Medical University

Harbin, Heilongjiang, China

The Second Affiliated Hospital of Harbin Medical University

Harbin, Heilongjiang, China

Hubei Cancer Hospita

Wuhan, Hubei, China

Union Hospital Tongji College Huazhong University of Science and Technology

Wuhan, Hubei, China

Hunan Provincial People's Hospital

Changsha, Hunan, China

Xiangya Hospital Central South University

Changsha, Hunan, China

Changzhou No.2 People's Hospital

Changzhou, Jiangsu, China

The Affiliated Hospital of Xuzhou Medical University

Xuzhou, Jiangsu, China

Northern Jiangsu People's Hospital

Yangzhou, Jiangsu, China

Anshan Cancer Hospital

Anshan, Liaoning, China

Ansteel Group General Hospital

Anshan, Liaoning, China

The First Affiliated Hospital of Jinzhou Medical University

Jinzhou, Liaoning, China

Shandong Provincial Hospital

Jinan, Shandong, China

The Affiliated Hospital of Qingdao University

Qingdao, Shandong, China

Yantai Yuhuangding Hospital

Yantai, Shandong, China

Zaozhuang Municipal Hospital

Zaozhuang, Shandong, China

First Affiliated Hospital of Xi'an Jiaotong University

Xi’an, Shanxi, China

Tianjin Medical University Cancer Institute and Hospital

Tianjin, Tianjin Municipality, China

First Affiliated Hospital of Xinjiang Medical University

Ürümqi, Xinjiang, China

Cancer Hospital Chinese Academy of Medical Sciences

Beijing, China

Fudan University Shanghai Cancer Center

Shanghai, China

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NCT03349762


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