Surgery With or Without Chemotherapy for Stage I NSCLC With Micropapillary Component ≥ 20%

This trial is investigating whether adding chemotherapy after surgery for early-stage lung cancer (stage I non-small cell lung cancer) that has a specific aggressive growth pattern (called micropapillary pattern, making up at least 20% of the tumor) improves outcomes compared to surgery alone. **You may be eligible if...** - Your lung cancer was completely removed by surgery and confirmed as stage I - The cancer was diagnosed as a specific type called micropapillary predominant lung adenocarcinoma - You are enrolled within 4 weeks of your surgery date - You have not had prior chemotherapy or radiation for lung cancer - You are in good overall health (performance status 0 or 1) - Women must not be pregnant or breastfeeding and must use effective contraception during the study **You may NOT be eligible if...** - You received chemotherapy or radiation before surgery - Your overall health is too poor to tolerate chemotherapy - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.