RecruitingNot ApplicableNCT03351868

FANCA Gene Transfer for Fanconi Anemia Using a High-safety, High-efficiency, Self-inactivating Lentiviral Vector

Gene Transfer for Fanconi Anemia Using a Self-inactivating Lentiviral Vector


Sponsor

Shenzhen Geno-Immune Medical Institute

Enrollment

10 participants

Start Date

Jun 1, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This is a Phase I/II clinical trial of gene therapy for treating Fanconi anemia using a self-inactivating lentiviral vector to functionally correct the defective gene. The objectives are to evaluate the safety and efficacy of the gene transfer clinical protocol.


Eligibility

Min Age: 2 YearsMax Age: 20 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Gene-modified autologous stem cells for people with fanconi anemia. The study is currently recruiting participants at 1 location. People eligible for this study include aged 2 Years to 20 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

GENETICGene-modified autologous stem cells

Infusion for 5x10\^6\~1x10\^7 per kilogram of body weight of gene-modified cells; or more infusions depending on the circumstances


Locations(1)

Shenzhen Geno-immune Medical Institute

Shenzhen, Guangdong, China

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NCT03351868


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