RecruitingNCT03375619

Long-term Follow-up Study of Patients Receiving CAR-T Cells


Sponsor

Medical College of Wisconsin

Enrollment

500 participants

Start Date

Dec 1, 2017

Study Type

OBSERVATIONAL

Conditions

Summary

This protocol is designed as a long-term follow-up study of participants who will receive CAR-T cells as part of a clinical trial at the Medical College of Wisconsin/ Froedtert Hospital. The clinical trials include the following: Phase 1 Study of CAR-20/19-T Cells in Patients with Relapsed Refractory B Cell Malignancies (NCT03019055); Phase I Trial of BCMA-TGF-BETA CAR-T Cells in Relapsed, Refractory Myeloma (NCT05976555); CAR20.19.22 T-cells in Relapsed, Refractory B-cell Malignancies (NCT05094206); LV20.19 CAR T-Cells in Combination With Pirtobrutinib for Relapsed, Refractory B-cell Malignancies (NCT05990465); CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell Malignancies (NCT04186520)


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria1

  • All participants who enrolled in a CAR-T study at Froedtert Hospital \& the Medical College of Wisconsin.

Interventions

OTHERLong-Term Follow-Up of Participants who Received CAR-T cells

No study drug is administered in this study. Participants who received CAR-T cells in a previous trial will be evaluated in this trial for long-term safety and efficacy.


Locations(1)

Froedtert Hospital & Medical College of Wisconsin

Milwaukee, Wisconsin, United States

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NCT03375619


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