RecruitingEarly Phase 1NCT03384537

Antimicrobial Effect of Tropolone Containing Versus Tropolone Free Mouthwash

Antimicrobial Effect of Tropolone Containing Versus Tropolone Free Mouthwash - Randomized Clinical Trail


Sponsor

Cairo University

Enrollment

30 participants

Start Date

Feb 8, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The objective of this study is to compare the effect of Tropolone containing mouthwash versus CHX 0.2% mouthwash in reducing intraoral microorganism. Randomized clinical trial study


Eligibility

Min Age: 18 YearsMax Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This trial is comparing the germ-killing (antimicrobial) effectiveness of two types of mouthwash — one containing a compound called tropolone and one without it — to see which is more effective at reducing harmful bacteria in the mouth. **You may be eligible if...** - You are between 18 and 45 years old - You appear to be in good health with no significant medical history - You are willing to temporarily stop your usual oral hygiene routine for 2 to 4 days before the experiment **You may NOT be eligible if...** - You have a compromised immune system or other serious health conditions - You have taken any antibiotics or antimicrobial agents in the last two weeks - You have dental braces, dentures, or other fixed or removable dental appliances - You have a high number of dental cavities (DMF score above 6) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

COMBINATION_PRODUCTListerine total care zero

reducing intra-oral cariogenic microorganism.

COMBINATION_PRODUCTChlorhexidine Mouthwash (0.2%).

Chlorhexidine Mouthwash (0.2%).


Locations(1)

Cairo University

Cairo, Egypt

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NCT03384537


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