RecruitingNCT03400345

Human Upper Extremity Allotransplantation: F/U Protocol

Human Upper Extremity Allotransplantation: Transplanted Patient Follow-Up Protocol

Sponsor

Johns Hopkins University

Enrollment

60 participants

Start Date

Jul 25, 2017

Study Type

OBSERVATIONAL

Conditions

Hand injuries Wounds and Injury Amputation, Traumatic

Summary

Upper extremity allotransplantation is a new procedure which is becoming more common in the United States. Ongoing data collection for research purposes is vital to the long-term assessment as to the safety of the procedure and accompanying immunosuppression protocol, as well as quantifying patient outcomes and changes in quality of life. For these reasons, The Johns Hopkins Hand/Arm Transplantation Team is interested in enrolling transplanted patients in a follow-up protocol to continue collecting informative data to further the field of vascularized composite allotransplantation.

Eligibility

Min Age: 18 YearsMax Age: 100 Years

Plain Language Summary

Simplified for easier understanding

This follow-up study monitors people who have received a transplanted upper limb (arm or hand) from a deceased donor — a rare and complex procedure called upper extremity allotransplantation. Since these transplants are uncommon, long-term follow-up data is essential for understanding how recipients function, their quality of life, potential complications, and the effectiveness of immunosuppressive treatments needed to prevent rejection. This is not a treatment study — it is a long-term monitoring protocol for those who already received a transplant at least five years ago. Participants undergo periodic assessments and may provide biopsy samples. You may be eligible if: - You have received an upper extremity (arm or hand) transplant from a donor - It has been at least 5 years since your transplant - You are 18 years of age or older - You are a U.S. citizen or equivalent - You agree to comply with the study protocol and immunomodulatory treatment You may NOT be eligible if: - You have not received an upper extremity transplant - You are unable or unwilling to comply with the protocol requirements Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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