RecruitingNCT03402139

Early Childhood Obesity Programming by Intrauterine Growth Restriction

Molecular Basis of Early Childhood Obesity Programming by Intrauterine Growth Restriction


Sponsor

Montefiore Medical Center

Enrollment

400 participants

Start Date

Sep 1, 2018

Study Type

OBSERVATIONAL

Conditions

Summary

The molecular mechanisms underlying developmental programming of childhood obesity remain poorly understood. Here, the investigators address major questions about early childhood obesity programming by studying CD3+ T-cells from intrauterine growth restricted (IUGR) newborns who have an increased risk for obesity and other metabolic disorders in adult life.


Eligibility

Min Age: 1 HourMax Age: 24 Months

Plain Language Summary

Simplified for easier understanding

This study is looking at whether babies who are born smaller than expected (due to poor growth in the womb) are at higher risk of becoming overweight during early childhood, and whether their metabolism differs from babies born at a normal weight. **You may be eligible if...** - You are a mother delivering at Montefiore Medical Center (Weiler Division) - Your baby was born full-term as a single baby (not twins or more) - Your baby is either smaller than expected for their gestational age (birth weight below the 10th percentile) OR a normal size for their gestational age - You are willing to participate and provide a representative sample **You may NOT be eligible if...** - Your baby has a known genetic disorder or birth defects - Your pregnancy had certain complications that would affect the study results Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Jack D. Weiler Hospital

The Bronx, New York, United States

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NCT03402139


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