RecruitingNot ApplicableNCT03422302

Continuous Positive Airway Pressure Device or Deep Inspiration Breath Hold in Reducing Tumor Motion in Patients Undergoing Stereotactic Body Radiation Therapy for Lung Cancer

Measuring the Effectiveness of a Continuous Positive Airway Pressure (CPAP) Device to Reduce Tumor Motion and Increase Lung Volume Expansion in Patients Undergoing Stereotactic Body Radiotherapy (SBRT) for Tumors That Move With Respiration

Sponsor

M.D. Anderson Cancer Center

Enrollment

30 participants

Start Date

Mar 16, 2018

Study Type

INTERVENTIONAL

Conditions

Lung Carcinoma Metastatic Malignant Neoplasm in the Lung Malignant Respiratory Tract Neoplasm

Summary

This pilot phase I/II trial studies how well a continuous positive airway pressure device or deep inspiration breath hold works in reducing tumor movement in patients undergoing stereotactic body radiation therapy (SBRT) for lung cancer. The continuous positive airway pressure device works by blowing air into the lungs while patients wear a face mask or nozzle to help expand their airways and lungs. Deep inspiration breath hold is a standard technique that uses active breath-holding to restrict movement of the body. Using a continuous positive airway pressure device may work better than deep inspiration breath hold in lowering the amount of tumor movement during stereotactic radiation body therapy.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two methods to keep lung tumors still during stereotactic body radiation therapy (SBRT) — a CPAP breathing device versus a technique where patients hold a deep breath — to see which better controls tumor movement and improves treatment accuracy. **You may be eligible if...** - You are receiving stereotactic body radiation therapy (SBRT) for lung cancer at MD Anderson Cancer Center - You are able to cooperate with breathing instructions - You have signed the study consent form **You may NOT be eligible if...** - You have a medical reason you cannot use a CPAP device - You have had recent facial, throat, stomach, or sinus surgery (within the last 3 months) - You have a lung condition called idiopathic pulmonary fibrosis (IPF) - You have reduced consciousness or are unable to cooperate - You have trauma or burns to your face Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.