RecruitingNCT03452774

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry


Sponsor

Massive Bio, Inc.

Enrollment

50,000 participants

Start Date

Jan 1, 2018

Study Type

OBSERVATIONAL

Conditions

Summary

International registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool, powered by a virtual tumor boards (VTB) program, and its clinical impact on pts with advanced cancer to facilitate clinical trial enrollment (CTE), as well as the financial impact, and potential outcomes of the intervention.


Eligibility

Plain Language Summary

Simplified for easier understanding

This study is using artificial intelligence to match cancer patients to the most suitable clinical trials based on the specific genetic mutations and biomarkers found in their tumors — and tracking outcomes over time to see how well AI-guided trial matching works. **You may be eligible if...** - You have a solid tumor or blood cancer (hematological malignancy) - Your tumor has been tested for specific genetic mutations, protein markers, or gene rearrangements through standard laboratory testing (such as IHC, PCR, FISH, or next-generation sequencing) - You are willing to have your biomarker data and clinical outcomes tracked in the registry **You may NOT be eligible if...** - Your tumor has not undergone biomarker or genetic testing - You are unwilling to participate in the registry or provide consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERClinical Trial Matching

Using a proprietary application programming interface (API) linked to existing electronic health records (EHR) platforms, individual clinical data is extracted, analyzed and matched to a parametric database of existing institutional and non-institutional CT. Machine learning algorithms allow for dynamic matching based on CT allocation and availability for optimized matching.


Locations(68)

Massive Bio SYNERGY-AI site

Birmingham, Alabama, United States

Massive Bio SYNERGY-AI site

Mobile, Alabama, United States

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Scottsdale, Arizona, United States

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Little Rock, Arkansas, United States

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Duarte, California, United States

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Irvine, California, United States

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La Jolla, California, United States

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Orange, California, United States

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San Francisco, California, United States

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Stanford, California, United States

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Aurora, Colorado, United States

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Denver, Colorado, United States

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Littleton, Colorado, United States

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Hartford, Connecticut, United States

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Norwalk, Connecticut, United States

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Newark, Delaware, United States

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Jacksonville, Florida, United States

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Miami, Florida, United States

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Tampa, Florida, United States

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Atlanta, Georgia, United States

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Savannah, Georgia, United States

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Boise, Idaho, United States

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Chicago, Illinois, United States

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Iowa City, Iowa, United States

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New Orleans, Louisiana, United States

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Scarborough, Maine, United States

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Baltimore, Maryland, United States

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Bethesda, Maryland, United States

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Silver Spring, Maryland, United States

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Towson, Maryland, United States

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Worcester, Massachusetts, United States

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Ann Arbor, Michigan, United States

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Lansing, Michigan, United States

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Duluth, Minnesota, United States

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Hattiesburg, Mississippi, United States

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Kansas City, Missouri, United States

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St Louis, Missouri, United States

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Billings, Montana, United States

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Omaha, Nebraska, United States

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New Brunswick, New Jersey, United States

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Albuquerque, New Mexico, United States

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Buffalo, New York, United States

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Hempstead, New York, United States

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Manhasset, New York, United States

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New York, New York, United States

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Staten Island, New York, United States

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Chapel Hill, North Carolina, United States

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Winston-Salem, North Carolina, United States

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Fargo, North Dakota, United States

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Cincinnati, Ohio, United States

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Columbus, Ohio, United States

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Mayfield Heights, Ohio, United States

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Tulsa, Oklahoma, United States

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Portland, Oregon, United States

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Philadelphia, Pennsylvania, United States

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Providence, Rhode Island, United States

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Greenville, South Carolina, United States

Massive Bio SYNERGY-AI site

Memphis, Tennessee, United States

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Nashville, Tennessee, United States

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Dallas, Texas, United States

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Houston, Texas, United States

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Temple, Texas, United States

Massive Bio SYNERGY-AI site

Salt Lake City, Utah, United States

Massive Bio SYNERGY-AI site

Charlottesville, Virginia, United States

Massive Bio SYNERGY-AI site

Seattle, Washington, United States

Massive Bio SYNERGY-AI site

Morgantown, West Virginia, United States

Massive Bio SYNERGY-AI site

Milwaukee, Wisconsin, United States

Massive Bio SYNERGY-AI site

San Juan, Puerto Rico

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NCT03452774


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