RecruitingNCT03458936

Resilience in Adolescent Development


Sponsor

University of Texas Southwestern Medical Center

Enrollment

1,500 participants

Start Date

Aug 17, 2016

Study Type

OBSERVATIONAL

Conditions

Summary

RAD is a 10-year natural history, longitudinal, prospective assessment study of a cohort of 2,500 participants (ages 10-24 years) that will help uncover the socio-demographic, lifestyle, clinical, psychological, and neurobiological factors that contribute to resilience among children, adolescents, and young adults at-risk for mood and anxiety disorders. As this is an exploratory study, we will assess a comprehensive panel of carefully selected participant specific parameters, including socio-demographic, life habits, clinical, biological, behavioral, neurophysiological, and neuroimaging. The study is designed to observe and collect factors associated with resilience in a non-invasive fashion; no interventions or treatments will be conducted during the project. Assessments will be conducted up to 4 times per year for up to 10 years, as well as a baseline visit. Study visits will be conducted in person whenever feasible but may be completed by phone/mail/computer, if an in-person visit is not possible.


Eligibility

Min Age: 10 YearsMax Age: 24 Years

Plain Language Summary

Simplified for easier understanding

This long-term research study is following young people aged 10 to 24 to understand why some teenagers and young adults develop mood disorders (like depression or bipolar disorder) while others stay mentally healthy, with the aim of identifying early warning signs and protective factors. **You may be eligible if...** - You are between 10 and 24 years old - You can speak, read, and understand English (parents/guardians may use Spanish during the consent process) - You fall into one of two groups: - At risk: you have a personal or family history of mental health disorders (anxiety, substance use, mood disorders in relatives, etc.) - Healthy: no psychiatric diagnoses in yourself or close family members **You may NOT be eligible if...** - You have a psychotic disorder (schizophrenia, schizoaffective disorder) or severe depression symptoms (PHQ-9 score of 10 or higher) - You cannot provide a stable home address - You have serious cognitive problems or are actively intoxicated - For the healthy control group: you or a close family member has any history of a mood disorder or mental health diagnosis Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.


Locations(1)

UT Southwestern Medical Center

Dallas, Texas, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT03458936


Related Trials