Value of LNG-IUS as Fertility-preserving Treatment of EAH and EC

This trial is studying whether a hormone-releasing IUD (LNG-IUS, like a Mirena device) can be used as a fertility-preserving treatment for young women with early-stage uterine (endometrial) cancer or abnormal uterine cell growth (endometrial atypical hyperplasia), instead of surgery that would prevent future pregnancy. **You may be eligible if...** - You are 40 years old or younger - You strongly wish to preserve your fertility - You have been diagnosed with either: - Early-stage, low-grade endometrial cancer (Grade 1, confined to the uterine lining, progesterone receptor positive), OR - Atypical endometrial hyperplasia (pre-cancerous uterine cell changes) - For endometrial cancer: your CA125/199 tumor markers are normal and MRI shows no spread outside the uterus **You may NOT be eligible if...** - You have allergies or contraindications to the drugs used - You have Lynch syndrome (a hereditary cancer condition) - You have reasons you cannot become pregnant - You have a serious infection in the genital tract or a uterine abnormality that prevents IUD placement - You refuse to attend follow-up appointments Talk to your doctor to see if this trial is right for you.