Evaluation of Human Immune Responses Vaccination in Patients With Lymphoma

This trial is studying how the immune system responds to vaccinations in people who have lymphoma (a type of blood cancer affecting the lymph nodes), to better understand how cancer and its treatments affect vaccine protection. **You may be eligible if...** - You have been diagnosed with a type of lymphoma, including B-cell lymphoma, chronic lymphocytic leukemia (CLL), mantle cell lymphoma, or T-cell lymphoma - You are currently receiving chemotherapy or a targeted drug called ibrutinib, or you are in remission - You are able to provide written consent and attend all study visits - Your basic blood test results fall within acceptable ranges **You may NOT be eligible if...** - Your lymphoma type does not fall within the listed categories - You are unable to follow the study procedures or attend visits - Your blood test results at screening are outside acceptable limits Talk to your doctor to see if this trial is right for you.