Fecal Microbiota Transplantation for Radiation Enteritis
Efficacy and Safety of Fecal Microbiota Transplantation in Radiation Enteritis
The Second Hospital of Nanjing Medical University
70 participants
Jan 7, 2018
INTERVENTIONAL
Conditions
Summary
Radiation enteritis is one of the most feared complications after abdominal or pelvic radiation therapy.The gut microbiota is considered to constitute a "microbial organ" which has pivotal roles in the intestinal diseases and body metabolism. Evidence from animal studies demonstrated the link between intestinal bacteria and radiation enteritis. This clinical trial aims to evaluate the efficacy and safety of fecal microbiota transplantation (FMT) for radiation enteritis.
Eligibility
Inclusion Criteria2
- age ≥18 years old;
- Radiation enteritis diagnosed by colonoscopy after finishing radiotherapy.
Exclusion Criteria4
- Patients who were pregnant or nursing;
- Patients who were unable or unwilling to undergo a gastroscopy;
- Patients who had gastrointestinal infection;
- Patients with cardiopulmonary failure.
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Interventions
Fecal microbiota transplantation for patients via nasointestinal tube or gastroscopy or colonic TET tube
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT03516461