Searching Biomarkers of Acute Intestinal Ischemic Injuries
Assistance Publique - Hôpitaux de Paris
556 participants
Nov 16, 2018
INTERVENTIONAL
Conditions
Summary
The aim of the SURVIBIO study is to characterize accurate biomarkers for acute mesenteric ischemia, in particular at early stages. In the study, the development of biomarkers will be based on the analysis of human biological samples from patients and controls that will be conserved in a biological library. Samples will be analysed in the Laboratory for Vascular Translational Sciences (LVTS, Inserm U1148), in the Department of Biochemistry (Pr Puy, Dr Peoc'h), in Paris V university , in Imperial College of London (Pr Dumas), in Jacques Monod Institute and in Maastricht University Medical Center . The candidate markers will be determined according to an a priori method (form markers already described in the literature) and with no a priori strategy using -omics methods.
Eligibility
Inclusion Criteria5
- age\> 18 years
- Acute abdominal pain requiring an injected abdominal injected CT scan, at best at non-injected / early arterial / portal time
- Admitted or attended in Beaujon and / or Bichat hospitals
- Patient covered by a social security scheme
- Written consent
Exclusion Criteria1
- • lack of abdominal CT scan
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Interventions
Two tubes of 5ml of blood will be collected for Serum collection, 3 tubes of 5 ml of blood taken for plasma collection and 2 tubes of 7 ml of blood taken for DNA collection
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT03518099