RecruitingNot ApplicableNCT03527992

Automated Oxygen Administration in Patients With Hypoxemic Pneumonia and Pleuropneumonia


Sponsor

University Hospital, Toulouse

Enrollment

128 participants

Start Date

Mar 9, 2018

Study Type

INTERVENTIONAL

Conditions

Summary

Hypoxemic pneumonia is a major cause of hospitalization in Pulmonology. The patient's dependency on oxygen prevents early discharge from the hospital. An automated oxygen therapy is a system that allows administration of oxygen with a flow that is automatically adjusted to the patient's saturation, which is continuously monitored. This system has proven to be particularly effective with chronic obstructive pulmonary disease (COPD) patients, by decreasing the time spent in hypoxia and hyperoxia, and by accelerating the weaning of oxygen. Our hypothesis is that automated oxygen therapy leads to a diminution on the length of hospital stay.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This French study tests an automated oxygen delivery system for patients hospitalized with pneumonia and low blood oxygen levels. Currently, nurses manually adjust oxygen flow for patients — but this can lead to periods when patients get too little or too much oxygen. An automated system constantly monitors oxygen saturation and adjusts delivery in real time, potentially improving outcomes and reducing nursing workload. The study compares automated versus standard manual oxygen administration in adult pneumonia patients. The study is open to adults newly admitted to hospital (within 48 hours) with community-acquired pneumonia and confirmed low oxygen levels, who do not yet require a ventilator or high-flow oxygen support. You may be eligible if: - You are an adult admitted to hospital within the past 48 hours - You have been diagnosed with pneumonia meeting defined criteria (respiratory symptoms, fever or low temperature, and chest X-ray findings) - Your blood oxygen level is low (SpO2 below 94% on room air or PaO2 below 60 mmHg) You may NOT be eligible if: - You acquired your pneumonia while already in the hospital - You have chronic respiratory failure or are on long-term oxygen therapy - You have active cancer - Your heart failure is contributing to your breathing difficulties - You need high-flow oxygen or breathing machine support from the start Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEO2 automated

In the "O2 automated" group, patients benefit from oxygen therapy via the "FreeO2" device. The O2 saturation target is set by the clinician on the device. Saturation is continuously sensed by an oximeter and the oxygen flow is automatically adjusted. The clinician has access to instantaneous values and trends of O2 and SpO2 flow rates.

DEVICEO2 standard

In the "O2 standard" group, patients benefit from oxygen therapy with nasal goggles or a high concentration mask. Saturation is continuously captured by an oximeter. The flow rate of oxygen, evaluated in L/min, is adapted according to local protocols (every 8 hours in conventional hospital services, continuous in intensive care


Locations(1)

CHU Larrey

Toulouse, France

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NCT03527992


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