Automated Oxygen Administration in Patients With Hypoxemic Pneumonia and Pleuropneumonia
University Hospital, Toulouse
128 participants
Mar 9, 2018
INTERVENTIONAL
Conditions
Summary
Hypoxemic pneumonia is a major cause of hospitalization in Pulmonology. The patient's dependency on oxygen prevents early discharge from the hospital. An automated oxygen therapy is a system that allows administration of oxygen with a flow that is automatically adjusted to the patient's saturation, which is continuously monitored. This system has proven to be particularly effective with chronic obstructive pulmonary disease (COPD) patients, by decreasing the time spent in hypoxia and hyperoxia, and by accelerating the weaning of oxygen. Our hypothesis is that automated oxygen therapy leads to a diminution on the length of hospital stay.
Eligibility
Inclusion Criteria8
- Adult
- Patient living at home or in an institution
- Patient hospitalized for less than 48 hours
- Pneumonia defined (according to the 2006 French-speaking infectious pneumology society (SPILF) criteria) by:
- respiratory functional symptoms (cough, sputum, dyspnea, chest pain) and
- Hyperthermia \>38,5°C or hypothermia \<36°C and
- Radiological Signs of Pneumonia
- Hypoxia : SpO2 \< 94% in ambient air and/or PaO2\< 60 mmHg in ambient air
Exclusion Criteria8
- Pneumonia acquired at the hospital.
- Patient hospitalized in another department more than 48 hours before admission
- Chronic respiratory failure
- Active neoplasia
- Patients undergoing oxygen therapy and / or long-term NIV
- Associated cardiac decompensation (clinical signs and / or NTproBNP\> 1800ng / mL) (3
- Initial Need for high flow oxygen therapy or ventilatory support (NIV, VI)
- Difficulties expected from home support.
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Interventions
In the "O2 automated" group, patients benefit from oxygen therapy via the "FreeO2" device. The O2 saturation target is set by the clinician on the device. Saturation is continuously sensed by an oximeter and the oxygen flow is automatically adjusted. The clinician has access to instantaneous values and trends of O2 and SpO2 flow rates.
In the "O2 standard" group, patients benefit from oxygen therapy with nasal goggles or a high concentration mask. Saturation is continuously captured by an oximeter. The flow rate of oxygen, evaluated in L/min, is adapted according to local protocols (every 8 hours in conventional hospital services, continuous in intensive care
Locations(1)
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NCT03527992