RecruitingNot ApplicableNCT03528226

Exercise Training and Endothelial Function in Type 1 Diabetes

Impact of Exercise Training on Endothelial Function in Adults With Type 1 Diabetes

Sponsor

University Hospital, Lille

Enrollment

34 participants

Start Date

Nov 12, 2019

Study Type

INTERVENTIONAL

Conditions

Type1diabetes

Summary

Endothelial dysfunction and vasoreactivity disorders are early subclinical complications of type 1 diabetes (T1D). In a preventive setting, in T1D patients still free of complications, the research of non-pharmacological interventions to improve endothelial function appears fundamental. In this randomized controlled trial, the effects of exercise training on endothelial function will be evaluated in T1D adults. Secondary objectives are to evaluate the exercise training effects on the micro and macrovascular function and exercise-induced tissue vasoreactivity and their possible neurometabolic consequences. An improvement in vascular function, particularly endothelium-dependent, as well as in neurometabolic profile, through this non-pharmacological strategy is expected

Eligibility

Min Age: 18 YearsMax Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This trial is studying whether regular exercise training can improve blood vessel function in people with type 1 diabetes who do not yet have diabetes-related complications, since poor blood vessel health is a major long-term risk in diabetes. **You may be eligible if...** - You are covered by social security (French healthcare system) - You have had type 1 diabetes for at least 1 year - You do not currently have any diabetes-related complications (no eye, kidney, nerve, or blood vessel damage) **You may NOT be eligible if...** - You were diagnosed with type 1 diabetes less than 1 year ago - You have type 2 diabetes, MODY, or any other form of diabetes - You already have complications from diabetes (such as eye, kidney, or nerve damage) - Your BMI is over 30 (obesity) - You smoke - You have high blood pressure - You have a condition that makes movement of the arms, legs, or torso painful or limited - You have any other active or recently treated chronic illness - You have had a head injury in the past Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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