RecruitingNCT03552926
Constitution of a Clinico-radiological Database and a Biobank for Patients With Lacunar Infarcts
Constitution of a Clinico-radiological Database and a Biobank for Patients With Lacunar Infarcts at Lariboisière Fernand-Widal and Sainte Anne Hospitals
Sponsor
Assistance Publique - Hôpitaux de Paris
Enrollment
500 participants
Start Date
Jun 6, 2018
Study Type
OBSERVATIONAL
Conditions
Summary
The aim of this study is to determine in patients with a recent lacunar strokes (\<15 days), the natural history of cognitive disturbances and disability.
Eligibility
Min Age: 18 Years
Inclusion Criteria7
- Age 18 years and above
- History of recent (less than 15 days) neurological deficit related to a small subcortical infarct (evidenced by medical history or physical examination)
- Diagnosis of recent small subcortical infarct on MRI (hyperintensity on diffusion-weighted imaging showing an infarction in the territory of one perforating artery) presumably responsible for the corresponding neurological deficit
- Lesion diameter mess than 20 mm
- Ability to comply with scheduled follow-up and annual neurological evaluation
- Affiliation to the national French health insurance (sécurité sociale)
- Signature of informed consent
Exclusion Criteria7
- Prior diagnosis of dementia according to DSM IV criteria
- Prior severe disability with Rankin scale ≥ 4
- Serious concomitant systemic disorder that can compromise the follow-up study;
- Leukoencephalopathy of non-vascular origin;
- Severe psychiatric disorder;
- Inability to obtain an informed signed consent from the patient or his/her family;
- Medical contraindication or refusal to undergo cerebral magnetic resonance scanning (MRI).
Interested in this trial?
Get notified about updates and connect with the research team.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT03552926