RecruitingNCT03558048

The Effect of IBD Flares on Serum PSA

The Effect of Inflammatory Bowel Disease Flares on Serum Prostate Specific Antigen


Sponsor

Northwestern University

Enrollment

400 participants

Start Date

Aug 1, 2019

Study Type

OBSERVATIONAL

Conditions

Summary

This study will measure Prostate Specific Antigen (PSA) values in men with Inflammatory Bowel Disease (IBD) before, during, and following a flare. In addition, the effect of any PSA increase will be analyzed and correlated to the location of disease (rectal vs. other). Study findings may help men with IBD by identifying pitfalls in prostate cancer screening for this population and help to stratify and understand the effect IBD has on the prostatic milieu. By optimizing how men with IBD are screened for prostate cancer, future unnecessary healthcare encounters and expenditures may be reduced for this patient group.


Eligibility

Sex: MALEMin Age: 40 YearsMax Age: 69 Years

Plain Language Summary

Simplified for easier understanding

This study investigates whether flare-ups (active episodes) of inflammatory bowel disease (IBD) — such as Crohn's disease or ulcerative colitis — affect the level of a protein in the blood called PSA, which is commonly used to screen for prostate cancer. **You may be eligible if...** - You are male and between 40 and 69 years old - You have a confirmed diagnosis of inflammatory bowel disease (Crohn's disease or ulcerative colitis) - You receive care at the Northwestern Memorial Hospital Gastroenterology Clinic **You may NOT be eligible if...** - You have a history of prostate cancer - You have previously had a prostate biopsy or a procedure called transurethral resection of the prostate Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTBlood draw

Subjects will have their blood drawn during clinic visits over the course of the study period to measure their serum prostate specific antigen levels.


Locations(1)

Northwestern Medicine

Chicago, Illinois, United States

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NCT03558048


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