Hemodynamics Monitoring During Lower Body Negative Pressure (LBNP) Induced Controlled Hypovolemia

This study monitors cardiovascular changes during controlled, simulated blood volume reduction using a technique called Lower Body Negative Pressure (LBNP). LBNP applies suction around the lower body to shift blood away from the heart, mimicking the effect of blood loss without any actual bleeding. By carefully tracking heart rate, blood pressure, and blood flow during this controlled procedure, researchers can test and validate monitoring devices and algorithms designed to detect early-stage hemorrhagic shock — a condition where blood loss becomes life-threatening. Findings could improve trauma care and military medicine. Only healthy adult volunteers aged 20–45 without any major health conditions are eligible for this study. You may be eligible if you: - Are between 20 and 45 years of age - Are in good health with no significant medical conditions You may NOT be eligible if you: - Are currently pregnant - Are under 20 years of age - Have coronary artery disease - Have diabetes - Have epilepsy - Have hypertension (high blood pressure) Talk to your doctor to see if this trial is right for you.