RecruitingNot ApplicableNCT03615690

The Influence of a Fasting Mimicking Diet on Ulcerative Colitis

Sponsor

Stanford University

Enrollment

75 participants

Start Date

Dec 15, 2020

Study Type

INTERVENTIONAL

Conditions

Ulcerative Colitis Inflammatory Bowel Disease Diet Modification

Summary

The purpose of this study is to see how a diet that mimics fasting effects inflammation in patients with mild to moderate Ulcerative Colitis (UC). The diet may allow users to receive the benefits of fasting while also being able to enjoy food (the ingredients of which are GRAS (generally recognized as safe) by the Food and Drug Administration (FDA). Research on dietary interventions and UC are very limited. Fasting mimicking diets (FMD) have been studied with support of the National Institute of Health and published in leading journals. This research investigates whether markers of inflammation decrease and/or quality of life increases after three cycles of a five-day period of the fasting mimicking diet, and may provide rationale for its use to treat UC.

Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This trial is studying whether a special short-term, low-calorie diet (called a fasting mimicking diet) can reduce inflammation and improve symptoms in people with ulcerative colitis (a condition causing chronic inflammation and ulcers in the large intestine). **You may be eligible if...** - You have been diagnosed with mild to moderate ulcerative colitis (a score between 2 and 7 on the partial Mayo Score) - You are between 18 and 70 years old **You may NOT be eligible if...** - You are pregnant, nursing, or planning to become pregnant - You have a nut allergy - Your BMI (body mass index) is below 18 (you are underweight) - You have diabetes and are taking insulin or blood sugar medications - You have a serious medical condition or are taking medications that cannot be used with a calorie-restricted diet - You have been severely weakened by illness or medical treatment Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.