RecruitingNCT03626194

Prospective Evaluation of the Efficacy and Safety of Endoscopic Tissue Apposition


Sponsor

University of Colorado, Denver

Enrollment

500 participants

Start Date

Dec 12, 2016

Study Type

OBSERVATIONAL

Conditions

Summary

This study is a prospective registry of patients undergoing endoscopic suturing and/or clip placement at our institution to assess the efficacy and safety of endoscopic tissue apposition. 1.1 Hypothesis: Endoscopic tissue apposition is efficacious and safe in the practice of gastrointestinal endoscopy. 1.2 Aims: To prospectively evaluate the efficacy and safety of Endoscopic Tissue Apposition in the practice of gastrointestinal endoscopy.


Eligibility

Min Age: 18 YearsMax Age: 89 Years

Inclusion Criteria11

  • Patients>18 years of age undergoing endoscopy for any of the following indications:
  • Indications for Tissue Apposition:
  • Closure of perforations
  • Closure of full thickness defects created during endoscopic full thickness resection
  • Closure of defects after endoscopic submucosal dissection and endoscopic mucosal resection
  • Closure of mucosotomy after Peroral Endoscopic Myotomy (POEM)
  • Stent fixation
  • Closure of fistulas
  • Natural Orifice Transluminal Endoscopic Surgery defect closures
  • Post-bariatric surgery gastrojejunal anastomosis and gastric pouch revision (transoral outlet repair)
  • Primary endoscopic sleeve gastroplasty

Exclusion Criteria6

  • Patients unable or unwilling to provide consent
  • Pregnant patients
  • Coagulation disorders (INR >1.8, platelet <50,000)
  • GI Bleeding
  • Hemodynamic instability
  • Enrollment in another device or drug study that may confound the results

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Locations(1)

University of Colorado Hospital

Aurora, Colorado, United States

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NCT03626194


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