Metformin for Pulmonary Hypertension HFpEF

This trial is testing whether metformin (a common diabetes medication) can improve outcomes in patients who have a specific combination of high blood pressure in the lungs (pulmonary hypertension) caused by heart failure with preserved pumping function (HFpEF), a condition often linked to metabolic syndrome (obesity, high blood pressure, and related conditions). **You may be eligible if...** - You have been diagnosed with pulmonary hypertension caused by heart failure (PH-HFpEF), confirmed by a heart catheterization procedure within the past 6 months - You have 3 or more features of metabolic syndrome, including: BMI over 30, high blood pressure, large waist circumference, elevated triglycerides, or low HDL (good) cholesterol **You may NOT be eligible if...** - You are already taking metformin - You have kidney problems that make metformin unsafe - You have type 1 diabetes - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.