RecruitingNCT03639285
Natural History, Diagnosis, and Outcomes for Leukodystrophies
Sponsor
University of Utah
Enrollment
600 participants
Start Date
Jan 19, 2007
Study Type
OBSERVATIONAL
Conditions
Summary
The goals of this protocol is to diagnose, care for, and understand the clinical histories and outcomes of people with leukodystrophies.
Eligibility
Inclusion Criteria3
- evidence by clinical exam, radiological findings, and/or testing, of an inherited leukodystrophy.
- be able to travel to the leukodystrophy clinic (at Primary Children's Hospital, Salt Lake City, Utah);
- be able to tolerate a general physical exam, and a neurological exam.
Exclusion Criteria4
- unable to be evaluated at the University of Utah Hospital or Primary Children's Hospital;
- refusal to sign study consent form;
- evidence or finding of another non-genetic cause of their condition;
- Persons with known white matter disease or lesions related to: birth injury or prenatal injury, multiple sclerosis, trauma, infection, immunization, or post-infectious effects (e.g. ADEM- acute disseminated encephalomyelitis), metabolic disturbance (e.g. Central pontine myelinolysis), neoplasms, primary rheumatologic diseases (e.g. Systemic lupus erythematosis), stroke, hypoxic-ischemic injury, drug or toxin effect, seizures, or endocrine disturbance.
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT03639285