RecruitingNot ApplicableNCT03648814
Intracameral Versus Intravitreal Bevacizumab Injection in NVG: RCT
Efficacy and Safety of Intracameral Versus Intravitreal Bevacizumab Injection as an Adjunctive Therapy Before Trabeculectomy With Mitomycin-C in Neovascular Glaucoma: A Prospective Randomized Trial
Sponsor
Prince of Songkla University
Enrollment
40 participants
Start Date
Aug 1, 2018
Study Type
INTERVENTIONAL
Conditions
Summary
To prospect studying the efficacy and safety of treating NVG with the intracameral versus the intravitreal injection of Bevacizumab.
Eligibility
Min Age: 18 Years
Inclusion Criteria7
- Diagnosis of neovascular glaucoma
- The patients having IOP \> 21 mmHg, having the indication for trabeculectomy
- The patients' age of at least 18-year-old
- The patients having visual potential at least hand motion.
- Present of NVI or NVA.
- Willing and able to provide informed consent to participate in the study
- Able to understand the purpose of the study, his/her role, and is available to return to the clinic/hospital for all required follow-up visits
Exclusion Criteria7
- One eye patient
- Patients having severe corneal edema or total hyphema obscure NVI or NVA view.
- Cannot obtain endothelial cell count.
- History of bevacizumab or fluorescence dye allergy.
- Active infectious ocular disease including endophthalmitis and corneal ulcer
- History of systemic disease including ischemic heart disease, cerebrovascular disease, end-stage renal disease, liver failure, uncontrolled hypertension
- Has or planning to be pregnant or breastfeeding
Interventions
PROCEDUREIntracameral injection
A/C injection of 1.25 mg/0.05 mL bevacizumab
PROCEDUREIntravitreal injection
Vitreous injection of 1.25 mg/0.05 mL bevacizumab
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT03648814