RecruitingNot ApplicableNCT03648814

Intracameral Versus Intravitreal Bevacizumab Injection in NVG: RCT

Efficacy and Safety of Intracameral Versus Intravitreal Bevacizumab Injection as an Adjunctive Therapy Before Trabeculectomy With Mitomycin-C in Neovascular Glaucoma: A Prospective Randomized Trial


Sponsor

Prince of Songkla University

Enrollment

40 participants

Start Date

Aug 1, 2018

Study Type

INTERVENTIONAL

Conditions

Summary

To prospect studying the efficacy and safety of treating NVG with the intracameral versus the intravitreal injection of Bevacizumab.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial is comparing two methods of injecting a drug called bevacizumab (which reduces abnormal blood vessel growth in the eye) in patients with a serious type of glaucoma caused by abnormal blood vessels, to see which injection method works better at lowering eye pressure. **You may be eligible if...** - You have been diagnosed with neovascular glaucoma (a serious type of glaucoma caused by abnormal blood vessels in the eye) - Your eye pressure is higher than 21 mmHg and you need a surgical procedure (trabeculectomy) - You are at least 18 years old - You have some remaining vision (at least able to detect hand movement) - You have abnormal blood vessels visible on the iris or in the eye's drainage angle - You are willing to participate and sign the consent form **You may NOT be eligible if...** - You have already had certain eye surgeries or treatments that would affect the results - You are unable to return for follow-up visits - You have other eye conditions that would interfere with the study Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREIntracameral injection

A/C injection of 1.25 mg/0.05 mL bevacizumab

PROCEDUREIntravitreal injection

Vitreous injection of 1.25 mg/0.05 mL bevacizumab


Locations(1)

Glaucoma unit , Department of Ophthalmology Faculty of Medicine Prince of Songkla University

Hat Yai, Changwat Songkhla, Thailand

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NCT03648814