RecruitingPhase 2NCT03673748

Treatment of Lupus Nephritis With Allogeneic Mesenchymal Stem Cells

Phase II, Double-Blind, Placebo-Controlled Clinical Trial to Evaluate Safety and Efficacy of Mesenchymal Stem Cells (MSV-allo) in the Treatment of Lupus Nephritis


Sponsor

Red de Terapia Celular

Enrollment

20 participants

Start Date

Dec 27, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to evaluate the safety and efficacy of mesenchymal stem cells (MSCs) obtained from bone marrow for the treatment of adults with active proliferative lupus nephritis. The objective of this study is to evaluate the efficacy of mesenchymal stem cells (MSCs) in achieving a full or partial response in the treatment of Lupus Nephritis (LN) during its induction period.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Mesenchymal stem cells (MSC) and a drug called Placebo for people with lupus erythematosus and lupus nephritis. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGMesenchymal stem cells (MSC)

Endovenous injection of MSV in saline solution

DRUGPlacebo

Endovenous injection of saline solution without cells


Locations(1)

University Hospital Río Hortega

Valladolid, Valladolid, Spain

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NCT03673748


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