RecruitingPhase 4NCT03684018

Two Dose Levels of Privigen in Pediatric CIDP

Randomized Study of Two Dose Levels of Privigen in Pediatric CIDP


Sponsor

CSL Behring

Enrollment

30 participants

Start Date

Feb 28, 2019

Study Type

INTERVENTIONAL

Conditions

Summary

A randomized, open-label, prospective, multicenter study designed to investigate 2 dose levels in pediatric subjects 2 to ≤ 17 years of age with confirmed or possible CIDP, either previously exposed to IVIG treatment or unexposed to IVIG treatment


Eligibility

Min Age: 2 YearsMax Age: 17 Years

Inclusion Criteria1

  • \- Male or female subjects 2 to ≤ 17 years of age with confirmed or possible CIDP.

Exclusion Criteria8

  • \- Absence of CIDP symptoms
  • History or family history of inherited neuropathy
  • Diagnosed developmental delay or regression
  • History of thrombotic episode
  • Known or suspected hypersensitivity to Privigen
  • Known allergic or other severe reactions to blood products
  • Female subject of childbearing potential either not using or not willing to use a medically reliable method of contraception or not sexually abstinent during the study
  • Pregnant or breastfeeding mother"

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Interventions

BIOLOGICALIgPro10

Normal human immunoglobulin G administered intravenously


Locations(9)

Phoenix Children's Hospital

Phoenix, Arizona, United States

Children's Hospital of Los Angeles

Los Angeles, California, United States

University of Iowa Hospitals and Clinics

Iowa City, Iowa, United States

Akron Children's Hospital

Akron, Ohio, United States

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, United States

Le Bonheur Children's Hospital

Memphis, Tennessee, United States

Neurology Rare Disease Center

Denton, Texas, United States

Children's Specialty Group

Norfolk, Virginia, United States

Seattle Children's Hospital

Seattle, Washington, United States

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NCT03684018