RecruitingPhase 2NCT03696680

Stereotactic Radiotherapy for Cerebral Metastases with Recent Hemorrhagic Signal

Stereotactic Radiotherapy for Cerebral Metastases with Recent Hemorrhagic Signal: Phase 2 Study in 2 Steps


Sponsor

Centre Francois Baclesse

Enrollment

46 participants

Start Date

Jan 16, 2019

Study Type

INTERVENTIONAL

Conditions

Summary

This prospective 2-stage, non-randomized Phase 2 trial evaluates the safety and efficacy of FSRT for the management of hemorrhagic brain metastases


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial is studying whether it is safe and effective to use a precise form of radiation called stereotactic radiotherapy to treat brain tumors (metastases from cancers elsewhere in the body) that show signs of bleeding inside the tumor, a situation that has historically been considered risky to treat with radiation. **You may be eligible if...** - You are 18 or older with 1 to 4 brain metastases (cancer that has spread to the brain from another cancer) - At least one brain tumor shows signs of bleeding on CT or MRI scans - The tumors are between 5 and 30 mm in size - Your primary cancer has been diagnosed by tissue biopsy - Your doctor's tumor board has agreed you are suitable for stereotactic radiotherapy - Your life expectancy is more than 6 months **You may NOT be eligible if...** - You have small cell lung cancer, germ cell tumors, lymphoma, leukemia, or myeloma - Your tumor is located in the brainstem - You have a neurodegenerative condition (like Alzheimer's or Parkinson's) - You are currently on certain anti-cancer therapies (with some exceptions) - The cancer has spread to the lining of the brain (meningeal involvement) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

RADIATIONFSRT Stereotactic radiation therapy

For each metastasis, dose of 30 Gy in 3 fractions at 10 Gy / fraction over 7 days


Locations(4)

Centre de la Baie

Avranches, France

Centre François Baclesse

Caen, France

Hospices Civils de Lyon

Lyon, France

Institut de Cancérologie de Lorraine

Nancy, France

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT03696680