RecruitingNCT03748069

Influenza Associated Aspergillosis In-depth Investigation

Unraveling the Pathogenesis of Influenza-associated Aspergillosis: a Single-center, Prospective Cohort Pilot Study


Sponsor

Universitaire Ziekenhuizen KU Leuven

Enrollment

45 participants

Start Date

Jan 18, 2019

Study Type

OBSERVATIONAL

Conditions

Summary

This trial is aimed to study the immunological and pathological characteristics of influenza versus non-influenza severe community-acquired pneumonia patients in ICU.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This Belgian study is investigating a serious complication called Influenza-Associated Pulmonary Aspergillosis (IAPA), where a fungal infection (Aspergillus) occurs in patients who are critically ill with influenza. Researchers are comparing ICU patients who have confirmed influenza with those who have other types of pneumonia, to understand why some influenza patients develop this deadly fungal infection. You may be eligible if: - You are over 18 years old - You have been admitted to the ICU with respiratory distress - You have a microbiologically confirmed influenza diagnosis (for the influenza group), OR you have confirmed community-acquired pneumonia without influenza (for the control group) You may NOT be eligible if: - You are under 18 years old - You are pregnant - You or your representative cannot or will not provide informed consent Talk to your ICU physician about whether you meet the criteria for this observation study, as enrollment typically happens during a critical illness hospitalization.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Universitaire Ziekenhuizen Leuven

Leuven, Belgium

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NCT03748069


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