RecruitingPhase 3NCT03770702

Statins and ARBs on Rheumatoid Activity

Investigational and Comparative Study Between the Anti-inflammatory Effectof Both Angiotensin Reeptor Blockers and Statins on Rheumatoid Arthritis Disease Activity on Egyptian Patients


Sponsor

Sherief Abd-Elsalam

Enrollment

45 participants

Start Date

Oct 1, 2018

Study Type

INTERVENTIONAL

Conditions

Summary

Investigational and comparative study between the anti-inflammatory effectof both angiotensin reeptor blockers and statins on rheumatoid arthritis disease activity on Egyptian patients


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating whether two types of widely used medications can help reduce inflammation and disease activity in patients with rheumatoid arthritis — a condition where the immune system mistakenly attacks the joints, causing pain, swelling, stiffness, and long-term joint damage. Statins are drugs most commonly used to lower cholesterol, but they also have anti-inflammatory effects that may benefit joints. ARBs (angiotensin receptor blockers) are blood pressure medications that may also help calm overactive immune responses. Researchers want to find out whether adding these medications to standard rheumatoid arthritis treatment leads to measurable improvements in inflammation markers and patient symptoms. **You may be eligible if...** - You have been diagnosed with rheumatoid arthritis - You are willing to participate and follow the study protocol **You may NOT be eligible if...** - You are pregnant or currently breastfeeding - You have significant liver problems that would affect how your body processes these medications - You have significant kidney (renal) problems Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGAngiotensin receptor blockers

Candesartan

DRUGStatins

Atorvastatin


Locations(1)

Sherief Abd-Elsalam

Tanta, Egypt

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NCT03770702


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