RecruitingPhase 3NCT03770936
Effect of Some Drugs on Liver Fibrosis
Clinical Study Evaluating the Efficacy of Renin Angiotensin System Inhibitors on the Extent of Liver Fibrosis in Patients With Chronic Hepatitis C
Sponsor
Sherief Abd-Elsalam
Enrollment
45 participants
Start Date
Oct 1, 2018
Study Type
INTERVENTIONAL
Conditions
Summary
Effect of Some Drugs on Liver Fibrosis
Eligibility
Min Age: 20 Years
Plain Language Summary
Simplified for easier understanding
This study is looking at how specific drugs affect the progression of liver fibrosis — the buildup of scar tissue in the liver — in patients with chronic hepatitis C, a long-lasting viral infection that slowly damages the liver over years or decades. Left untreated, liver fibrosis can progress to cirrhosis (severe scarring) and even liver failure or cancer. The goal is to understand whether these treatments can slow or reverse the scarring process, potentially improving long-term liver health. Patients will be monitored through blood tests and possibly liver assessments throughout the study.
**You may be eligible if...**
- You have been diagnosed with chronic hepatitis C (an ongoing liver infection caused by the hepatitis C virus)
- You have signs of liver fibrosis (scarring)
**You may NOT be eligible if...**
- You have acute (sudden and short-term) hepatitis rather than the chronic form
- You have thalassemia (an inherited blood disorder that affects red blood cells)
Talk to your doctor to see if this trial is right for you.
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
DRUGCandesartan
Candesartan 8 mg/day
DRUGRamipril
ramipril 1.25 mg/day
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT03770936
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