RecruitingPhase 3NCT03770936

Effect of Some Drugs on Liver Fibrosis

Clinical Study Evaluating the Efficacy of Renin Angiotensin System Inhibitors on the Extent of Liver Fibrosis in Patients With Chronic Hepatitis C


Sponsor

Sherief Abd-Elsalam

Enrollment

45 participants

Start Date

Oct 1, 2018

Study Type

INTERVENTIONAL

Conditions

Summary

Effect of Some Drugs on Liver Fibrosis


Eligibility

Min Age: 20 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at how specific drugs affect the progression of liver fibrosis — the buildup of scar tissue in the liver — in patients with chronic hepatitis C, a long-lasting viral infection that slowly damages the liver over years or decades. Left untreated, liver fibrosis can progress to cirrhosis (severe scarring) and even liver failure or cancer. The goal is to understand whether these treatments can slow or reverse the scarring process, potentially improving long-term liver health. Patients will be monitored through blood tests and possibly liver assessments throughout the study. **You may be eligible if...** - You have been diagnosed with chronic hepatitis C (an ongoing liver infection caused by the hepatitis C virus) - You have signs of liver fibrosis (scarring) **You may NOT be eligible if...** - You have acute (sudden and short-term) hepatitis rather than the chronic form - You have thalassemia (an inherited blood disorder that affects red blood cells) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGCandesartan

Candesartan 8 mg/day

DRUGRamipril

ramipril 1.25 mg/day


Locations(1)

Sherief Abd-Elsalam

Tanta, Egypt

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NCT03770936


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