RecruitingNCT03774420

Post Operative Cognitive Dysfunction After Breast Surgery

Post-Operative Cognitive Dysfunction After Breast Surgery: Incidence and Relation With Common Intraoperative Neuromonitoring Data and Concentration of Propofol and Remifentanil Infused With Targeted Controlled Infusion (TCI )in Women With Laryngeal Mask Airway


Sponsor

University of Padova

Enrollment

200 participants

Start Date

Jul 3, 2019

Study Type

OBSERVATIONAL

Conditions

Summary

Aim of this trial is to define if Post-Operative Cognitive Dysfunction, detected analyzing changes between pre-operative and post-operative Neurocognitive Test, and Postoperative Delirium, relate to concentration of effector's site concentration of propofol and remifentanil TCI and to the common intraoperative neuromonitoring values as well as to Pupillometry values (in particular Pupil Diameter, Pupil Latency, and Maximum Contraction Velcoity).


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria2

  • General Anaesthesia delivered with Propofol and Remifentanil with Targeted Controlled Infusion
  • Use of Laryngeal Mask airway

Exclusion Criteria2

  • Neurological pathologies
  • Haemodynamical instability during surgery

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Locations(1)

Treviso Regional Hospital

Treviso, TV, Italy

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NCT03774420


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