Enhancing Renal Graft Function During Donor Anesthesia

This study is testing different anesthesia techniques used during kidney donation surgery from a living donor to see whether certain approaches can better protect the function of the donated kidney — which could lead to improved outcomes for transplant recipients. Specifically, the research is looking at how the anesthesia given to the donor during surgery affects how well the kidney works once it is transplanted into the recipient. By optimizing this part of the process, doctors hope to extend graft survival and reduce complications after kidney transplantation. **You may be eligible if...** - You have end-stage kidney disease (your kidneys have nearly or completely failed) - You are scheduled to receive a kidney from a living donor **You may NOT be eligible if...** - You have severe heart problems that would make anesthesia risky - You have severe liver problems - You have a blood clotting disorder (coagulopathy) that would complicate surgery or recovery Talk to your doctor to see if this trial is right for you.