RecruitingNCT03784924

EDRN Prostate MRI Biomarker Study

EDRN Prostate MRI Biomarker Study and Reference Set


Sponsor

University of Michigan

Enrollment

950 participants

Start Date

Feb 4, 2019

Study Type

OBSERVATIONAL

Conditions

Summary

The commercialization of MRI fusion biopsies has resulted in a dramatic increase in the use of MRI imaging for prostate cancer. How best to use MRI in the initial prostate biopsy setting given the availability of validated prostate cancer early detection markers is uncertain.This study will allow investigators to determine if prostate MRI is superior to validated panel of laboratory biomarkers (e.g. PCA3, PSA and TMPRSS2:ERG) in the initial biopsy setting.


Eligibility

Sex: MALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is evaluating whether MRI imaging of the prostate, combined with specific protein markers measured in blood and urine, can more accurately detect and characterize prostate cancer in men being evaluated for a first-time diagnosis. Currently, prostate biopsies are commonly done but can miss cancers or lead to unnecessary procedures. This research aims to build a better, less invasive diagnostic picture by combining imaging with biomarkers, potentially reducing the need for biopsies while catching clinically significant cancers earlier. **You may be eligible if...** - You are a man with suspected but not yet confirmed prostate cancer - You are already scheduled (or being scheduled) for a prostate biopsy as part of routine clinical care **You may NOT be eligible if...** - You are unable to have blood or urine samples collected according to protocol - You cannot tolerate a prostate MRI or it cannot be done properly - You have already received a prostate cancer diagnosis Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTMRI prostate

MRI and laboratory biomarkers


Locations(1)

University of Michigan

Ann Arbor, Michigan, United States

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NCT03784924


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