Study of Different Therapeutic Strategies in Hydatidiform Mole With Lung Nodule
Study of Different Therapeutic Strategies in Hydatidiform Mole With Lung Nodule,A Prospective Multicentre Randomized Controlled Trial
Women's Hospital School Of Medicine Zhejiang University
30 participants
Dec 24, 2018
INTERVENTIONAL
Conditions
Summary
The purpose of present study is to provide clinical evidences for the appropriate management of molar pregnancy with lung nodule. The hydatidiform mole patients with lung nodule ≥1.0cm will be randomized into 2 groups: A. treated with chemotherapy immediately, B. follow up until hCG level met FIGO diagnostic criteria of GTN (B1) or hCG level declined to normal spontaneously (B2). Lung nodule \<1.0cm will directly treated as group C
Eligibility
Plain Language Summary
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Interventions
the follow up group would be naturely didived into 2 subgroups depending the hCG regression degree.
First line treatments:low risk:Methotrexate or ACTD; high risk:EMA-CO
Locations(1)
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NCT03785574