Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer
Phase III Randomized Trial of Proton Beam Therapy (PBT) Versus Intensity Modulated Photon Radiotherapy (IMRT) for the Treatment of Esophageal Cancer
NRG Oncology
300 participants
Jun 26, 2019
INTERVENTIONAL
Conditions
Summary
This trial studies how well proton beam radiation therapy compared with intensity modulated photon radiotherapy works in treating patients with stage I-IVA esophageal cancer. Proton beam radiation therapy uses a beam of protons (rather than x-rays) to send radiation inside the body to the tumor without damaging much of the healthy tissue around it. Intensity modulated photon radiotherapy uses high-energy x-rays to deliver radiation directly to the tumor without damaging much of the healthy tissue around it. It is not yet known whether proton beam therapy or intensity modulated photon radiotherapy will work better in treating patients with esophageal cancer.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
Undergo blood sample collection
Oral
Given IV
Undergo CT or PET/CT
IV
Undergo esophagectomy
IV
Undergo IMRT
Oral
IV
Given IV
Undergo PET/CT
Undergo PBT
Ancillary studies
Ancillary studies
Locations(95)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT03801876