HoLEP Prior to Radiation Therapy for Patients With LUTS/Retention and Concurrent Prostate Cancer

This study is evaluating whether performing a minimally invasive prostate procedure called HoLEP (a laser surgery that removes excess prostate tissue to improve urine flow) before radiation therapy can safely reduce urinary problems in men with prostate cancer who also have significant difficulty urinating. **You may be eligible if...** - You are 18 years or older - You have been diagnosed with prostate cancer - You have bothersome urinary symptoms: a high symptom score, a large amount of urine remaining in your bladder after urinating, or you require a catheter to urinate - You are scheduled to receive radiation therapy for prostate cancer **You may NOT be eligible if...** - You do not have significant urinary symptoms or retention - You have already received radiation therapy for prostate cancer - You have conditions that make the HoLEP procedure unsafe Talk to your doctor to see if this trial is right for you.