RecruitingNot ApplicableNCT03803332

A Trial Comparing Interpersonal Therapy to Exposure Therapy for PTSD Due to Military Sexual Trauma (MST) in Male and Female Military Personnel

A Non-Inferiority Randomized Controlled Clinical Trial Comparing Interpersonal Therapy to Exposure Therapy for PTSD Consequent to Military Sexual Trauma


Sponsor

Weill Medical College of Cornell University

Enrollment

208 participants

Start Date

Mar 9, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to compare two kinds of therapy for Posttraumatic Stress Disorder (PTSD): exposure therapy (ET) and Interpersonal Psychotherapy (IPT). The results of this study will allow us to see if IPT and ET are equally effective in treating PTSD due to Military Sexual Trauma, with the long-term goal of making PTSD treatment effective for as many people as possible.


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Inclusion Criteria6

  • English-speaking
  • Military Sexual Trauma (MST) survivors, with MST defined as actual or threatened sexual violence, from Vietnam era to current Operation Iraqi Freedom/Operation Enduring Freedom/Operation New Dawn
  • Diagnosed with PTSD consequent to MST, with a minimum CAPS score > 40
  • Medically stable at time of study enrollment (for persons with chronic injuries and that any disability present does not prevent attendance of weekly outpatient therapy sessions)
  • Ability to provide informed consent and function at an intellectual level sufficient to allow accurate completion of all assessment instruments
  • Stable on psychotropic medication for the prior 60 days

Exclusion Criteria5

  • Lifetime or current diagnosis of schizophrenia or other psychotic disorder, bipolar disorder
  • Participation in a clinical trial or concurrent evidence-based treatment for MST-related psychiatric conditions or PTSD during the previous 3 months
  • Current evidence of significant unstable medical illness or organic brain impairment such that the patient could not attend sessions regularly or complete assessments
  • Patients who in the investigator's judgment pose a current homicidal or suicidal risk
  • Current or history of substance dependence in the past 90 days.

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Interventions

BEHAVIORALExposure Therapy

Psychotherapy including imaginal and in vivo exposure for PTSD.

BEHAVIORALInterpersonal Psychotherapy

Psychotherapy that focuses on the effects of PTSD on current interpersonal functioning.


Locations(1)

Weill Cornell Medicine

New York, New York, United States

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NCT03803332


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