RecruitingEarly Phase 1NCT03810651

Pencil Beam Scanning in Patients With Renal Tumors

Pilot Study of Pencil Beam Scanning Proton Beam Radiation Therapy in Patients With Renal Tumors


Sponsor

Children's Hospital of Philadelphia

Enrollment

28 participants

Start Date

Dec 26, 2017

Study Type

INTERVENTIONAL

Conditions

Summary

This is a pilot study to assess acute toxicity in patients receiving flank irradiation using proton therapy for renal tumors.


Eligibility

Min Age: 0 YearsMax Age: 30 Years

Plain Language Summary

Simplified for easier understanding

This trial is studying whether a very precise type of proton radiation treatment (called pencil beam scanning — which targets tumors with extreme accuracy to protect surrounding healthy tissue) is safe and effective for children with kidney cancer (Wilms tumor or clear cell sarcoma of the kidney). **You may be eligible if...** - You are under 30 years old - You have been diagnosed with Wilms tumor or clear cell sarcoma of the kidney (CCSK) - Your doctors have recommended radiation therapy as part of your standard care - You have specific cancer staging or features that require radiation (e.g., Stage III, anaplasia, or CCSK diagnosis) **You may NOT be eligible if...** - You have had prior radiation to the same area - You have not yet received chemotherapy for your kidney cancer diagnosis - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERProton beam radiation using pencil beam scanning

Proton beam radiation using pencil beam scanning, characterized by Bragg peak dose deposition and high conformality of dose to target regions


Locations(1)

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, United States

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NCT03810651


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