RecruitingEarly Phase 1NCT03810651
Pencil Beam Scanning in Patients With Renal Tumors
Pilot Study of Pencil Beam Scanning Proton Beam Radiation Therapy in Patients With Renal Tumors
Sponsor
Children's Hospital of Philadelphia
Enrollment
28 participants
Start Date
Dec 26, 2017
Study Type
INTERVENTIONAL
Conditions
Summary
This is a pilot study to assess acute toxicity in patients receiving flank irradiation using proton therapy for renal tumors.
Eligibility
Min Age: 0 YearsMax Age: 30 Years
Inclusion Criteria7
- Less than 30 years of age
- Diagnosis
- a. Any patient with Wilms tumor or clear cell sarcoma of the kidney who would require radiation therapy as standard of care including
- Any patient with favorable histology (FH), stage III disease
- Any patient with focal or diffuse anaplasia
- Any patient with CCSK
- The patient is a candidate for external beam radiotherapy based on standard of care for treatment of Wilms tumor or CCSK
Exclusion Criteria3
- Prior radiotherapy to the region of the study cancer
- Chemotherapy administered for diagnosis of Wilms tumor or CCSK
- Pregnant or breastfeeding
Interventions
OTHERProton beam radiation using pencil beam scanning
Proton beam radiation using pencil beam scanning, characterized by Bragg peak dose deposition and high conformality of dose to target regions
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT03810651
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