Reproducibility of Dual Beam Doppler Fourier-domain Optical Coherence Tomography in Healthy Subjects
Short- and Long-term Reproducibility of Dual Beam Doppler Fourier-domain Optical Coherence Tomography Measurements in Healthy Subjects - a Pilot Study
Medical University of Vienna
20 participants
Nov 19, 2018
INTERVENTIONAL
Conditions
Summary
Dual beam Doppler Fourier-domain Optical coherence tomography (DOCT) is a noninvasive technique to quantify total retinal blood flow. To enable further development of this technique it is essential to assess short- and long-term reproducibility of DOCT blood flow measurements.
Eligibility
Inclusion Criteria4
- Men and women aged between 18 and 35 years
- Non-smokers
- Normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant
- Normal ophthalmic findings, ametropy \< 3 Dpt.
Exclusion Criteria6
- Regular use of medication, abuse of alcoholic beverages, participation in a clinical trial in the 3 weeks preceding the study
- Treatment in the previous 3 weeks with any drug (except contraceptives)
- Symptoms of a clinically relevant illness in the 3 weeks before the first study day
- Blood donation during the previous 3 weeks
- Pregnancy, planned pregnancy or lactating
- History or family history of epilepsia
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Interventions
Retinal blood flow will be assessed using DOCT.
Retinal vessel diameters and oxygen saturation will be measured with the DVA device.
Retinal morphology will be imaged using OCT.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT03821467