RecruitingPhase 4NCT03826524

Epinephrine Dose: Optimal Versus Standard Evaluation Trial

CanROC Epinephrine Dose: Optimal Versus Standard Evaluation Trial (CanROC EpiDOSE Trial)

Sponsor

Unity Health Toronto

Enrollment

3,790 participants

Start Date

May 24, 2023

Study Type

INTERVENTIONAL

Conditions

Ventricular Fibrillation Sudden Cardiac Arrest Cardiac Arrest, Out-Of-Hospital Ventricular Tachycardia-Pulseless

Summary

The objective of this randomized controlled trial is to evaluate the effectiveness of a low cumulative dose of epinephrine compared to a standard cumulative dose of epinephrine during resuscitation from ventricular fibrillation (VF) or ventricular tachycardia (VT) in adult out-of-hospital cardiac arrest (OHCA) patients.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Epinephrine for people with cardiac arrest, out-of-hospital, sudden cardiac arrest, and other related conditions. The study is currently recruiting participants at 8 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGEpinephrine

Epinephrine 1mg 1:10000 (10cc) per dose

Locations(8)

British Columbia Emergency Health Services (BCEHS)

Victoria, British Columbia, Canada

Peel Regional Paramedic Services

Brampton, Ontario, Canada

Middlesex-London Paramedic Service

London, Ontario, Canada

Halton Region Paramedic Services

Oakville, Ontario, Canada

Ottawa Paramedic Services

Ottawa, Ontario, Canada

Superior North Emergency Medical Services

Thunder Bay, Ontario, Canada

Essex-Windsor Emergency Health Services

Windsor, Ontario, Canada

Medavie Health Services West

Saskatoon, Saskatchewan, Canada

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT03826524

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