RecruitingPhase 4NCT03844360

Dose Individualization of Antineoplastic Drugs and Anti-Infective Drug in Children With Hematoplastic Disease


Sponsor

Wei Zhao

Enrollment

1,500 participants

Start Date

Jan 31, 2016

Study Type

INTERVENTIONAL

Conditions

Summary

The investigators' purpose was to assess the feasibility of dosage individualization of the commonly used antineoplastic drugs and anti-infective drugs in children with hematoplastic disease.


Eligibility

Min Age: 1 DayMax Age: 18 Years

Inclusion Criteria2

  • Patients must be diagnosed with hematological neoplasms
  • Antineoplastic drugs or anti-infective drugs used as part of regular treatment

Exclusion Criteria2

  • expected survival time less than the treatment cycle;
  • patients with other factors that researcher considers unsuitable for inclusion.

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Interventions

DRUGBortezomib

bortezomib was administered follow the doctor's advice.

DRUGEltrombopag

eltrombopag was administered follow the doctor's advice.

DRUGImatinib

imatinib was administered follow the doctor's advice.

DRUGdasatinib

dasatinib was administered follow the doctor's advice.

DRUGPegaspargase

pegaspargase was administered follow the doctor's advice.

DRUGAnti-Infective Drugs

anti-infective drugs was administered follow the doctor's advice.

DRUGPEGylated Recombinant Human Granulocyte Colony-Stimulating Factor

pegaspargase was administered follow the doctor's advice.


Locations(2)

Department of Pediatrics, the Affiliated Hospital of Xuzhou Medical University

Xuzhou, Jiangsu, China

State Key Laboratory of Experimental Haematology, Department of Paediatric Haematology, Institute of Haematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

Tanjin, Tianjin Municipality, China

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NCT03844360


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