RecruitingNCT03853733

Hypofractionated Palliative Radiotherapy in Patients With Advanced Non-operable Rectal Cancer

Palliative Hypofractionated Radiotherapy in Non-operable Rectal Cancer: A Retrospective Study

Sponsor

Consorci Sanitari de Terrassa

Enrollment

50 participants

Start Date

Oct 1, 2016

Study Type

OBSERVATIONAL

Conditions

Rectal Cancer

Summary

Many patients with rectal cancer were not candidates for surgical resection because advanced age, comorbidities, or multiple synchronous metastases. In this scenario only comfort measures or different palliative radiotherapy regimens are applied, from single doses to treatments lasting several weeks. The aim of this prospective study is to describe the preliminary results of our protocol of hypofractionated palliative radiotherapy in patients with non-operable rectal cancer.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is looking back at records of patients with rectal or sigmoid colon cancer who could not have surgery due to their age, health conditions, or advanced disease, and were instead treated with a short course of radiation therapy (39Gy in 13 sessions), to understand how well this palliative treatment controlled symptoms. **You may be eligible if...** - You have rectal or sigmoid colon cancer - You were NOT a candidate for surgical removal of your cancer (due to older age, significant health problems, or cancer that had already spread widely) - You are 18 years or older - You received the specific radiation dose regimen of 39Gy in 13 fractions as part of your treatment **You may NOT be eligible if...** - Your cancer was in a different part of the colon (not rectum or sigmoid) - You are younger than 18 - You received chemotherapy at the same time as radiation - You were actually a candidate for surgery (curative intent) after radiation Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATIONrectal cancer radiotherapy

Conformal three-dimensional radiotherapy to deliver to the primary tumor and the enlarged pelvic nodes a total dose of 39Gy in 13 sessions of 3Gy in 17 days.