RecruitingNCT03853733

Hypofractionated Palliative Radiotherapy in Patients With Advanced Non-operable Rectal Cancer

Palliative Hypofractionated Radiotherapy in Non-operable Rectal Cancer: A Retrospective Study


Sponsor

Consorci Sanitari de Terrassa

Enrollment

50 participants

Start Date

Oct 1, 2016

Study Type

OBSERVATIONAL

Conditions

Summary

Many patients with rectal cancer were not candidates for surgical resection because advanced age, comorbidities, or multiple synchronous metastases. In this scenario only comfort measures or different palliative radiotherapy regimens are applied, from single doses to treatments lasting several weeks. The aim of this prospective study is to describe the preliminary results of our protocol of hypofractionated palliative radiotherapy in patients with non-operable rectal cancer.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Patients with rectal or sigmoidal cancer who were not candidates for surgical resection because advanced age, comorbidities, or multiple synchronous metastases at the time of diagnosis
  • Patients with = or \> 18 years old
  • Patients treated with a radiotherapy dose of 39Gy in 13 fractions of 3 Gy

Exclusion Criteria4

  • Patients with a non rectum or sigma colo-rectal cancer.
  • Patients with \<18 years old.
  • Patients treated with concurrent chemotherapy
  • Patients candidates for surgical resection after radiotherapy

Interventions

RADIATIONrectal cancer radiotherapy

Conformal three-dimensional radiotherapy to deliver to the primary tumor and the enlarged pelvic nodes a total dose of 39Gy in 13 sessions of 3Gy in 17 days.


Locations(1)

Consorci Sanitari de Terrassa

Terrassa, Catalonia, Spain

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NCT03853733


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